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TL1 (T32) Research Education Program Return to TRANSFORM homepage

The approach to the training of pre-doctoral students who will fulfill the vision of independently contributing to multi- and interdisciplinary clinical and translational (C/T) research is challenging. The fragmentation of research into specialty and then subspecialty perspectives has resulted in breadth requirements for PhD degrees becoming increasingly narrowed, as we ensure adequate specialization knowledge within each rapidly advancing discipline.

In evaluating the quality and breadth of existing training programs at Columbia, we seek to further enhance C/T pre-doctoral training at CUMC and to counter-act the narrowing of PhD specialties. The health profession will require, in the near future, PhD scientists who possess the complex, specialty knowledge of their basic science discipline, but who additionally possess the skill set and know-how to rapidly translate and apply their research into clinically meaningful application. We also need superbly trained clinical researchers who understand the fundamentals of "wet-bench" translational science, and can collaborate with investigators working in those fields. For example, a sophisticated appreciation of the cellular or molecular mechanisms underlying a given clinical research interest enables the formulation of more informed clinical research questions and the implementation of more sophisticated and targeted diagnostic and treatment approaches.

To accomplish these goals, we have established the Research Education Program, in which pre-doctoral students currently enrolled as Howard Hughes Medical Institute scholars or doctoral candidates in Epidemiology will be offered a small set of focused, additional courses and practica to provide new, critical C/T educational experiences. This pre-doctoral training opportunity will prepare a new generation of scientists to understand the methods and techniques used across the full range of the pathway from the bench to the bedside and ultimately to the community, and this training will also formally prepare these scientists to participate in, and create, interdisciplinary science.

The Clinical or Translational Research Education Certificate program is a one year program which includes a year-long course with interdisciplinary science rounds, an ethics course, grant-writing training, and various symposia. It is open to second year or higher students who are enrolled as Howard Hughes Medical Institute scholars or doctoral candidates in Epidemiology at Columbia, and provides up to four awards per year providing a stipend and funds to put towards tuition, travel and fees.

TRANSFORM Research Education Program Director


Karina W. Davidson

Karina W. Davidson, PhD
Herbert Irving Associate Professor in Medicine and Psychiatry
Director, Center for Behavioral Cardiovascular Health
Associate Director, Columbia CTSA

You may download an application here, or contact Sophia Li, TRANSFORM Administrative Manager.

Research Education Program Participants

Dana Alessi, Cellular, Molecular and Biophysical Studies
Integrated Program in Cellular, Molecular and Biomedical Studies

Ambar Grijalva, Nutritional and Metabolic Biology

Annina DeLeo, Cellular, Molecular, and Biomedical Studies
MicroRNA Regulation of the switch from Qiuescent to Activated cell state in Adult Neural Stem Cells

Meghan Work, Epidemiology
Breast Cancer Risk Factors and Intermediate Markers and Associations with Tumor Characteristics

Graduates of the Program

Sarah Canetta, Neurobiology and Behavior
Type III Nrg1-erbB Signaling in Nociception

Julie Choe, Sociomedical Sciences
Bridging the technology divide - Translational science and technological innovation in medicine

Zhi-De Deng, Electrical Engineering
Field Shaping and Coil Design for Transcranial Magnetic Stimulation (TMS)

Roxanne Dutia, Institute for Human Nutrition
Hypothalamic Melancontin Regulation of Energy Balance and Metabolism

Erin Harelton, Pharmacology
TASK-1 in Arrhythmogenesis Downstream of PAF Signaling

Millie Hepburn-Smith, Nursing
Reduction of Stroke Risk in Minority Women

Allan Just, Environmental Health Sciences
A Molecular Epidemiologic Study of Endocrine Disruptors and Pediatric Asthma

Nowai Keleekai, Nursing
Study of Mental Health Services of an HIV-positive Incarcerated Population

Kristen Klemenhagen, Neurobiology & Behavior
Developmental Role of the 5-HT1A Receptor in Establishing Adult Anxiety Behavior

Jorge Luna, Epidemiology
Acute and chronic infectious predictors of stroke.

Ann Madsen, Epidemiology
Common Cause Model for Genetic Epidemiology and Risk-Factor Epidemiology: Laying the Foundation for Integration

David Malito, Neurobiology
Calcium Channel Mutations in Heart Arrythmias and Autism

Russell McBride, Epidemiology
Genetic Similarities in DNA Repair Polymorphisms between BRCA2 and HNPCC syndromic cancer families

Arthur Mikhno, Biomedical Engineering
Non-Invasive and cost effective quantification of Positron Emission Tomography data

Megan Niedzwiecki, Environmental Health Sciences
Title: TBD (Molecular Epidemiology)

Stan Okrasinski, Biomedical Engineering
In vivo clinical validation of myocardial elastography

James Papizan, Nutrition and Metabolic Biology
Structure-function analysis of the essential islet regulatory factor, Nkx2.2

Kelly Ruggles, Nutrition and Metabolic Biology
Cellular fatty acid toxicity extrapolating yeast

Alex Smolak, School of Social Work
Culturally Congruent HIV Risk Reduction with Male Muslim Migrant Workers in Kazakhstan

Gary That Vi Yu, Biostatistics
Evaluating and predicting clinical effectiveness of risk factors in CHD

Hideaki Yano, Pharmacology
Understanding Mechanism of Dopamine Mediated HIV-Entry in NeuroAIDS

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