On October 1, 2006, Columbia University was one of the first 12 institutions in the country to receive a Clinical and Translational Science Award (CTSA). Combined with increased support from our long-time benefactors, Herbert and Florence Irving, this award enabled the former Irving Center for Clinical Research (GCRC) to evolve into the Irving Institute for Clinical and Translational Research thereby becoming the academic and intellectual home for the next generation of clinical and translational research investigators at CUMC. Continuing the tradition of clinical research first started at Columbia University in 1928, the focus of the Irving Institute is to transform the way clinical and translational research is conducted, enabling medical investigators to develop new treatments faster, and to deliver those treatments to patients more efficiently and more effectively.

Senior faculty funded by the Irving Institute provide leadership and serve as mentors for both junior faculty and trainees of the Irving Institute. They provide outstanding support and resources to Institute users including research in biomedical informatics, biostatistical and clinical trial design, bioethics, regulatory issues, patient-oriented research, and core laboratory resources, among many others. As part of the CTSA program, the Irving Institute houses an integrated educational program that includes a patient-oriented master’s degree, a novel K12 mentored research program in multi- and interdisciplinary research, and a predoctoral clinical and translational certificate. The chief goal of the Irving Institute and CTSA is to more directly utilize medical research advances to benefit patients and the community, converting knowledge into practice.

Our goals include:
  • Changing the culture of research so that individual investigators can seek out and easily collaborate with other investigators in both similar and different areas of biomedical research.
  • Effecting change in the promotions and tenure process so that multi- and interdisciplinary clinical and translational research and mentorship is recognized appropriately.
  • Training and educating MDs and PhDs who will become agents of change as they translate basic science findings to the treatment of people.
  • Improving the health and well-being of our patients and neighbors in Northern Manhattan.

In pursuit of these goals, we are joined by a dedicated group of Associate Directors and Executive Leaders.

Henry N. Ginsberg, MD
Herbert and Florence Irving Professor of Medicine
Associate Dean for Clinical and Translational Research
Director and Principal Investigator,
Irving Institute for Clinical and Translational Research

Melissa D. Begg, ScD
Professor of Clinical Biostatistics
Associate Dean for Interdisciplinary Programs
Co-Director, Irving Institute for Clinical and Translational Research