Two-week Course in Designing a Clinical Research Project

Who:  Pediatrics residents who have chosen a mentor and clinical question
When:  Usually early in PGY2
Capacity:  Four to six residents, in order to provide individual attention

Content:  Residents review summaries of published research (chosen to highlight different types of studies and different possible errors and interpretation issues. Each resident then develops their research proposal for the IRB with comments and advice from CRR faculty. The rotation ends with the residents making formal presentations of their proposals.

Present Status:  15-18 of 24 Pediatrics residents do 3-4 rotations in July-September.
History:  Was mandatory for Internal Medicine residents for 20 years. Discontinued two years back with the advent of a palliative care rotation.

Online material: http://biomath.info/Protocols/Peds/
Power (sample size) Calculation Module


Helping Young Investigators Become Self-Sufficient in Statistics

Based on our work with residents, we have observed that, unlike young researchers who join a laboratory and learn how to do data management and statistical analysis from benchmates and other colleagues, residents and clinical fellows are often on their own, having to seek outside help, when it comes to analyzing their research data. A 6-hour hands-on lecture module has been developed to teach researchers to organize data in Excel, decide on the appropriate statistical approach, and carry out the analyses on their own using the free software package R. Working on their laptops, they learn data manipulation and graphing using Excel, and then statistical analyses using R, beginning with t-tests and going on through anova and linear regression to complex procedures including stepwise logistic regression and Cox proportional hazards modeling. Assistants are present to help with any difficulties. The module was tried with Pediatrics residents last year and is being refined now with Pediatrics fellows.