KL2 Mentored Career Development Award

The TRANSFORM KL2 Scholars Mentored Career Development program serves as a "bridge" by which young junior faculty can achieve research independence. It is open to junior faculty with professorial titles (clinical- or tenure-track).

To gain the knowledge and skills necessary to function effectively on interdisciplinary research teams, KL2 Scholars will complete a rigorous training program that guarantees exposure to a wide range of clinical and translational research methods in both classroom and experiential settings. The key features of the training program include

  • a research Master's degree (the MS/POR,) with traditional classroom training;
  • a mentored research project; and
  • participation in multidisciplinary seminars and colloquia.

With funding from the NIH CTSA award, the Irving Institute for Clinical and Translational Research seeks to promote high-quality research, enhance the integration of clinical and translational science, advance the latest proven health care approaches and deliver them more quickly to the patient community. An integral part of this effort is the KL2 Mentored Career Development Program. The KL2 program serves as a "bridge" by which young junior faculty can achieve research independence in multidisciplinary research settings.

Phase I Applications Due Date: January 15, 2019
Phase II Selected Applicants Announced: February 28, 2019
Phase II Applications Due Date: April 1, 2019
Anticipated Award Start Date: June 1, 2020

KL2 Information
KL2 Phase I Application
KL2 Phase I Recommendation form


If you have any questions regarding the KL2 program, please send an e-mail to Sophia Li Ferry, Senior Program Manager.

TRANSFORM KL2 Scholars Program Directors

Melissa D. Begg Melissa D. Begg, ScD
Vice Provost for Academic Programs, Columbia University
Professor of Biostatistics, Mailman School of Public Health
Co-Director, Irving Institute for Clinical & Translational Research Columbia University
Daichi Daichi Shimbo, MD
Associate Professor of Medicine
Director, Translational Lab at the Center of Behavioral Cardiovascular Health
Director of Cardiovascular Physiology Research, Cardiovascular Ultrasound Laboratories Ewig Clinical Scholar


KL2/TRANSFORM Activity/Event

2017-2018 Dates

POR Colloquium Tuesdays, 3pm-4pm
KL2 Meetings and Presentations Third Tuesday of every month (with exceptions) - 4:00PM-6:00PM
KL2 Mentor/Trainee Evaluations Due March 1, 2018
KL2 Individual Progress Reports Due Semi-annually
Annual ACRT/SCTS CTSA Conference in Washington, DC

Wednesday, April 19 - Friday, April 21, 2018

Research Poster Day Last day of spring semester, POR colloquim
KL2 Exit Surveys/Evaluations Due July, 2018


Current Awardees

Marwah Abdalla, MD, MPH
Obstructive Sleep Apnea and Masked Hypertension

Melissa Accordino, MD
SWOG 1703CD: Randomized Multicenter Trial Comparing Tumor Marker Directed Diesase Monitoring Versus Usual Care in the Monitoring of Metastatic Hormone Receptor Positive Breast Cancer Patients

Bernard Chang, MD, MPH
Test of an alternative Emergency Department management strategy for TIA and minor stroke patients; an explanatory and guideline-relevant RCT to reduce PTSD after TIA and minor stroke

Lauren Chernick, MD
Test of an alternative Emergency Department management strategy for TIA and minor stroke patients; an explanatory and guideline-relevant RCT to reduce PTSD after TIA and minor stroke

Hilda Fernandez, MD
Genomic disorders, CKD, and neurocognitive status in children

Arthur Garan, MD
Optimizing Function of Cardiac Rhythm Devices in Patients Supported by Left Ventricular Assist Device

Minjae Kim, MD, MS
Improving risk prediction of perioperative morbidity and mortality: role of intraoperative variables

Meghna Trivedi, MD
Patient and physician knowledge, attitudes, and expectations of genomic testing to inform treatment decisions for advanced cancer

Past Awardees

Roy Alcalay, MD, MS
The Role of Glucocerebrosidase in Parkinson Disease

Carmela Alcantara, PhD, MA
Prognostic Risk of Sleep Deficiency After Acute Coronary Syndrome

Natalie Bello, MD, MPH
Relaxin and Subsequent Hypertension Risk in Women with a History of Pregnancy Induced Hypertension

Brett Anderson, MD, MBA, MS
Effects of Surgeon Technical Skill on Outcome and Resource Utilization for Children with Congenital Heart Disease

Neeraj Badjatia, MD
Metabolic Impact of Therapeutic Normothermia after Subarachnoid Hemorrhage

Jennifer Woo Baidal, MD, MPH
Accelerating Point-of-Care Testing to Diagnose Pediatric Non-Alcoholic Fatty Liver Disease

Matthew Baldwin, MD, MS
Improving Critical Illness Survivorship for Older Adults

Allegra Broft, MD
Bulimia Nervosa and Dopamine - A link to addictions?

Jiook Cha, PhD
A Developmental Neuroimaging Study of Fear Generalization and Pediatric Anxiety

Hyunmi Choi, MD, MS
A prospective study to improve epilepsy management utilizing decision analysis

Catherine Clelland, PhD
Association of GCH1 with schizophrenia: Genetic and functional analysis and novel treatment strategies

Eileen Connolly, MD, PhD, MS
Utilizing combined chemoradiation therapy to improve the locoregional control of locally advanced triple negative breast cancer

Katherine Crew, MD
Vitamin D and Breast Cancer Risk and Survival

Kristen Klemenhagen, PhD
Cognitive and Emotional Pattern Separation: A Possible Therapeutic Target for Anxiety and Depression

Thuy-Tien Dam, MD
Hormonal Mediators of Body Composition and Frailty Transitions

Peter Dayan, MD, MS
Multicenter ED study of children with apparently unprovoked seizures

Andrew Einstein, MD, PhD
Estimating and Reducing Radiation Risk in Cardiac Imaging

Daniel Freedberg, MD, MS
Adverse effects of proton pump inhibitors on the gastrointestinal health of children

Kathleen Friel, PhD
Mechanisms of cerebral palsy recovery induced by balancing motor cortex activity

Jemima Frimpong, PhD, MPH
Workplace Diversity in Substance Abuse Treatment Programs and Disparities in Patient Outcomes

Sheng-fu (Larry) Lo, MD, MHS
Development of Patient-Derived Xenograft Models of Chordomas in Humanized Mice to Investigate in Vivo Effect of Immunotherapy: A step toward Precision Medicine in Chordoma Treatment

Ragy Girgis, MD, MS                                  
Antipsychotic Binding to the D3 and D2 Receptors in Schizophrenia: a PET study using 11<-(+)-PHNO

Heather Greenlee, ND, PhD
Effects of Coenzyme Q10 on Preventing Cardiotoxicity in Breast Cancer Patients Receiving Doxorubicin Treatment

Quan Hoang, MD, PhD
Pathologic Myopia: Natural History and Novel Approaches in Therapy

Guillermo Horga, MD
Neural mechanisms of sensory predictions in schizophrenia with hallucinations

Vaidehi Jobanputra, PhD
High Resolution Genomic Microarrays for Genotype-Phenotype Correlations of Constitutional Chromosome Abnormalities

Kevin Kalinsky, MD, MS
Monitoring Neoadjuvant Anti-Angiogenics in Breast Cancer with Optical Tomography

Krzysztof Kiryluk, MD
Genetic determinants of IgA1 glycosylation defects in IgA Nephropathy (IgAN)

Benjamin Lebwohl, MD, MS
Quality Issues in the Diagnosis of Celiac Disease

Teresa Lee, MD, MS
Identification of Novel Genetic Causes of Infantile Cardiomyopathy

David Lederer, MD, MS
Explaining racial and ethnic disparities in idiopathic pulmonary fibrosis

Deborah Levy, MD, MS
Neurocognitive function in childhood-onset Systemic Lupus Erythematosus (cSLE)

Stephanie Lovinsky-Desir, MD
The Impact of Physical Activity Level on Environmental and Epigenetic Mechanisms in Asthma

Jonathan Lu, MD
Measurement of Cardiac Repolarization Reserve Using Patient-Specific Induced Pluripotent Stem Cells

Matthew Maurer, MD
Tensirolimus, erlotinib, and cisplatin combined to treat triple negative breast cancer patients

Thomas Nickolas, MD
Bone Quality and Mechanical Competence in Chronic Kidney Disease

Christopher Ochner, PhD
Changes in Brain Activation and Appetite-Related Hormones following Bariatric Surgery for Obesity

Sameer Patel, MD
Improving Vancomycin Use in Hospitalized Children

J. Michael Schmidt, MD
Prediction of Delayed Cerebral Ischemia after Subarachnoid Hemorrhage using Multivariate Time Series Classification Models

Scott Schobel, MD
Testing novel mechanisms of antipsychotic therapy withhigh-resolution functional magnetic resonance imaging in humans and mouse models of disease

Rebecca Schnall, RN, PhD
Using Queuing Theory to Improve HIV Testing in the Emergency Department

Rachel Shelton PhD, MPH
Treatment Decision-Making among Stage II Colorectal Cancer Patients

Abby Siegel, MD
NASH, metabolic syndrome, and HCC outcomes

Aviva Sopher, MD, MS
Effect of Metformin on IR, NAFLD and Body Composition in adolescents with PCOS

Marisa Spann, PhD, MPH
Early brain networks of attention and language as precursors to childhood neuropsychiatric disorders

Alexandra Sporn, MD
Neurocircuitry of autism spectrum disorders: fMRI and TMS studies

Gissette Reyes-Soffer, MD
Understanding the Regulation and Metabolism of Ip(a) Levels, an Understudied Risk Factor for Cardiovascular Disease

Badri Vardarajan, PhD, MS
Whole exome sequencing in Caribbean Hispanic families to identify coding variants in Alzheimer's disease

Elizabeth Verna, MD, MS
Serum Lipopolysaccharide Measurement to Predict Hepatic Fibrosis in Liver Transplant Recipients with Hepatitis

Ismee Williams, MD, MS
Prenatal effects of congenital heart disease on neurodevelopmental outcome

Gabrielle Page-Wilson, MD
Utilization of Proopiomelanocortin and Agouti-related Protein ELISAs for the Differential Diagnosis and Evaluation of ACTH-dependent Cushing’s syndrome.

Hannah Wunsch, MD, MSc
Evaluation of the utility of head CTs in general medical and surgical intensive care patients

Siqin Ye, MD, MS
Patient health information preference and statin therapy

Angela Yoon, DDS, MPH
Biomarkers for non-invasive oral cancer screening