The Irving Institute is currently accepting applications for several pilot funding programs.

Applications are due November 1, 2017
TRx pre-proposals are due December 1, 2017

Visit here for more information.

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2017 Precision Medicine Pilot Awards – Announced February 7, 2017

Investigative Team Department Research Topic
Jonathan Barasch, MD, PhD
Peter Sims, PhD
Krzysztof Kiryluk, MD
Christopher Anderson, MD
Pablo Gonzalez-Camara, PhD
Raul Rabadan, PhD
Medicine/Nephrology
Systems Biology
Medicine/Nephrology
Urology
Systems Biology
Systems Biology
Definition of Acute Kidney Injury at Single Cell Resolution
Barry Fine, MD, PhD
Gordana Vunjak-Novakovic, PhD
Emily Chen, PhD
Emmanuel Zorn, PhD
Paolo Colombo, MD
Nicholas Tatonetti, PhD
Medicine/Cardiology
Biomedical Engineering
Pharmacology
Medicine/Cardiology
Medicine/Cardiology
Biomedical Informatics
Modeling and Prediction of Primary Graft Dysfunction After Heart Transplant
Arnold Han, MD, PhD
Yufeng Shen, PhD
Kelley Yan, MD, PhD
Paul Oberstein, MD
Emmanuel Zorn, PhD
Sacher Adrian, MD
Medicine/Digestive and Liver Diseases
Biomedical Informatics
Medicine/Digestive and Liver Diseases
Hematology/Oncology
Medicine/Cardiology
Hematology/Oncology
Precision T-cell receptor-based cancer therapies
Vivek Iyer, MD
Hasan Garan, MD
Angelo Biviano, MD
Medicine/Cardiology Patient-specific computational models to guide atrial fibrillation therapy
Mercedes Martinez, MD
Megan Sykes, MD
Elizabeth Verna, MD
Pediatrics/Gastroenterology, Hepatology and Nutrition
Hematology/Oncology
Medicine/Digestive and Liver Diseases
A TCR sequencing approach to understanding graft dysfunction following transplantation for autoimmune liver disease

 

2016 Precision Medicine Pilot Awards – Announced February 5, 2016

Investigative Team Department Research Topic
Changchun Deng, MD, PhD (PI)
Peter Sims, PhD
Donald Landry, MD, PhD
Karthik Ganapathi, PhD
Medicine
Systems Biology
Medicine
Pathology and Cell Biology
Precision Delivery of c-Myc-Silencing Therapy by Identifying Genes Sensitive to Dual Inhibition of PI3Kδ and CK1ε
Pamela Freda, MD (PI)
Peter Canoll, MD, PhD
Jeffrey Bruce, MD
Yufeng Shen, PhD
Zhezhen Jin, PhD
Alexander Khandji, MD
Medicine
Pathology and Cell Biology
Neurosurgery
Biomedical Informatics
Biostatistics
Radiology
Development of a personalized approach to the evaluation and treatment of acromegaly: Integration of genomic, histopathologic and radiographic data with a large, existing prospective clinical outcomes dataset
Kenneth Olive, PhD (PI)
Andrea Califano, PhD
Medicine
Systems Biology
Precision targeting of pancreatic cancer regulatory networks
Simone Sanna-Cherchi, MD (PI)
Iuliana Ionite-Laza, PhD
Barry Honig, PhD, MS
Medicine
Biostatistics
Biochemistry / Molecular Biophysics
A functional modeling framework to identify actionable alleles from clinical exome sequencing
Marcella Walker, MD, MS (PI)
David Goldstein, PhD
Edward Guo, PhD, MS
Xiaolin Zhu, MB
Medicine
Genetics and Development
Biomedical Engineering
Institute for Genomic Medicine
A genetic approach toward individualizing the assessment of osteoporosis

 

2015 Precision Medicine Pilot Awardees – Announced December 10, 2014

Collaborators Department Research Topic
Ying Kuen K. Cheung, PhD (PI)
Joseph Jurcic, MD
Shing Lee, PhD
Min Qian, PhD
Gary Schwartz, MD
Biostatistics
Medicine
Biostatistics
Biostatistics
Medicine
Model Enrichment in Reinforcement Learning for Optimal Personalized and Patient Centered Cancer Treatments
Thomas Diacovo, MD (PI)
Samuel Sia, PhD
Pediatrics
Biomedical Engineering
Personalized Pharmacology for Neonatal Cardiac Patients at Risk for Arterial Thrombotic Events
Krzysztof Kiryluk, MD, MS (PI)
David J. Cohen, MD
Vivette D. D’Agati, MD
Jean C. Emond, MD
Susan Restaino, MD
Elizabeth Verna, MD
Chunhua Weng, PhD
Emmanuel Zorn, PhD
Medicine
Medicine
Pathology and Cell Biology
Surgery
Medicine
Medicine
Bioinformatics
Medicine
Donor-Recipient Genomic Incompatibilities in Solid Organ Transplant
Heath Morris, MD (PI)
Yufeng Shen, PhD
Megan Sykes, MD
Medicine
Biomedical Informatics
Medicine
A New Biomarker of Kidney Transplant Outcomes: Tracking the Fate of Donor-Reactive T Cells in the Blood and Urine
Ruth Ottman, PhD (PI)
Cigdem Inan Akman, MD
Hyunmi Choi, MD, MS
Arthur Jeff Goldsmith, PhD
Dale C. Hesdorffer, PhD
Karolynn Siegel, PhD
Annapurna Poduri, MD, PhD
Epidemiology
Neurology
Neurology
Biostatistics
Epidemiology
Social Work
Harvard Medical School
Clinical and Psychosocial Utility of Whole Exome Sequencing in Pediatric Epilepsy
Tilla Worgall, MD, PhD (PI)
Qiao Lin, PhD
Milan Stojanovic, PhD
Pathology and Cell Biology
Mechanical Engineering
Medicine
Personalized Aptamers for MRD in Multiple Myeloma